Selective Androgen Receptor Modulators (SARMs): Muscle Growth Without Side Effects?,Former Steroid Users Have Low Testosterone,Anabolic steroids increase exercise tolerance,Effects of Androgenic-Anabolic Steroids in Athletes
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Synthetic anabolic agents: steroids and nonsteroidal selective androgen receptor modulators.
The central role of testosterone in the development of male characteristics, as well as its beneficial effects on physical performance and muscle growth, has led to the search for synthetic alternatives with improved pharmacological profiles. Hundreds of steroidal analogs have been prepared with a superior oral bioavailability, which should also possess reduced undesirable effects. However, onl...
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Background & Objectives: There have been several reports showing that the rate of anabolic-androgenic steroids abuse has increased in athlete and non-athlete adolescents. Therefore, the objective of this study was to assess, attitude and awareness of side-effects of these drugs in male bodybuilders. Methods: 227 bodybuilders completed a tridimensional questionnaire that investigated demographi...
متن کاملMale osteoporosis and androgenic therapy: from testosterone to SARMs.
As in the women, male osteoporosis represents an important social problem, amplified by the increasing life expectance.Differently from women, 50% of male osteoporosis is secondary to treatments and/or diseases that make mandatory their search through an accurate clinical investigations in every newly diagnosed osteoporotic men. Male osteoporosis is frequently underdiagnosed and consequently un...
متن کاملSelective androgen receptor modulators in preclinical and clinical development
Androgen receptor (AR) plays a critical role in the function of several organs including primary and accessory sexual organs, skeletal muscle, and bone, making it a desirable therapeutic target. Selective androgen receptor modulators (SARMs) bind to the AR and demonstrate osteo- and myo-anabolic activity; however, unlike testosterone and other anabolic steroids, these nonsteroidal agents produc...
متن کاملComparison of Behavioral Activation-Inhibition Systems and Sense of Coherence in Bodybuilders with and Without Use of Anabolic-Androgenic Steroids
Abstract Introduction: Anabolic-androgenic steroids are one of the powerful drugs that cause long-term hormonal and psychological changes that can have a wide range of side effects for the athletes. Objective: The purpose of this study was to compare the Behavioral Activation-Inhibition Systems and Sense of Coherence in Bodybuilders with and without Use Anabolic-Androgenic Steroids. Material...
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